No matter how much you love your suitcase-sized purse, eventually you’re going to feel the effects weighing on your muscles and they may begin to tear. Fast-forward 5 to 10 years and you’ve got shoulder numbness and tingling from pinched nerves, back pain, and arthritis of the neck. To combat the effects, sort through your purse (you’ll be amazed at all of the random things you’ve accumulated).  Switch sides every 10 minutes when walking around, and every hour or so, drop the bag and roll your shoulders backward and then forward to relieve muscle tension. Consider switching to smaller bags at least a few times a week to lighten the load and the wear and tear.